The Effectiveness of Moringa (Moringa oleifera L.) and Gedi Leaves (Abelmoschus Manihot L.) Combination Towards Total Cholesterol Levels in Hypercholesterolemia induced Wistar rats (Rattus norvegicus)

HAELSA, Sonya (2023) The Effectiveness of Moringa (Moringa oleifera L.) and Gedi Leaves (Abelmoschus Manihot L.) Combination Towards Total Cholesterol Levels in Hypercholesterolemia induced Wistar rats (Rattus norvegicus). Skripsi thesis, Universitas Jenderal Soedirman.

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Abstract

Treating hypercholesterolemia can minimize the other cardiovascular disease. Treatment can be handled both medically or using traditional medicine. Substances contained in Moringa and Gedi leaves as a medical medicine can lowering total cholesterol. This research is a true experiment with pre-test and post-test designs. The samples were divided into 6 groups, namely group A (Positive control), group B (negative control), group C (80 mg/200gBw: 30 mg/200 gBW) group D (160 mg/200 gBW: 30 mg/200 gBW), group E (80 mg/200 gBW: 60mg/200 gBW) and group F control group with simvastatin. Experimental animals were given a HFD for 14 days and then given treatment according to the dose for 14 days. One Way ANOVA and Post-hoc Duncan were used to analyze the total cholesterol level data. All treatment groups can reduce total cholesterol levels. Group C can reduce with an average difference of 139.5, Group D =123.5, Group E = 125.75 and Group F = 92.75 The result showed that group C (1:1) has the most effective effect on decreasing total cholesterol level by with the smallest and optimal dose that can lower cholesterol levels the most

Item Type:	Thesis (Skripsi)
Nomor Inventaris:	I23019
Uncontrolled Keywords:	Moringa Leaf, Gedi leaf, High Fat Diet (HFD), Hypercholesterolemia, Simvastatin
Subjects:	C > C317 Cholesterol
Divisions:	Fakultas Ilmu Ilmu Kesehatan > S1 Ilmu Keperawatan
Depositing User:	Mrs HAELSA Sonya
Date Deposited:	13 Feb 2023 01:34
Last Modified:	13 Feb 2023 01:34
URI:	http://repository.unsoed.ac.id/id/eprint/20002

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