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The Effectiveness Combination of Moringa (Moringa oleifera L.) and Gedi Leaves (Abelmoschus manihot L.) in High Fat Induced Wistar Rats (Rattus norvegicus)

JUNA, Zahra Tiara (2023) The Effectiveness Combination of Moringa (Moringa oleifera L.) and Gedi Leaves (Abelmoschus manihot L.) in High Fat Induced Wistar Rats (Rattus norvegicus). Skripsi thesis, Universitas Jenderal Soedirman.

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Abstract

Background : The high fat content of fast food can lead to obesity and other degenerative diseases. This disease can affect coronary heart disease, which can be identified by rising VLDL levels. Moringa and Gedi leaves are two plants that are used to reduce VLDL levels in the body. Methods : This research used a true experimental design with pretest and posttest with control group design. The samples were divided into 6 groups: group A positive control, group B negative control, groups C, D, and E were given boiled water from Moringa and Gedi leaves at a 1: 1 dose (30 mg/ 200 gBW Moringa : 80 mg/ 200 gBW Gedi), 1: 2. (30 mg/200 gBW Moringa: 160 mg Gedi), 2:1 dose (60 mg Moringa: 80 mg Gedi), and group F as a comparison group (Simvastatin 0.18 mg/200gBW). Rats were induced by HFD and given intervention. VLDL levels data obtained was tested with One Way ANOVA followed by Duncan's Posthoc. Results: VLDL decreased least in Groups A and B. VLDL decreased slightly in groups D, E, and F. Group C at 1:1 dose reduced VLDL by 30.90 mg/dL, causing it the most effective.

Item Type: Thesis (Skripsi)
Nomor Inventaris: I23069
Uncontrolled Keywords: Moringa leaves, Gedi leaves, High Fat Diet, Very low Density Lipoprotein, Simvastatine, Wistar rats
Subjects: D > D163 Diet
M > M168 Medical botany
Divisions: Fakultas Ilmu Ilmu Kesehatan > S1 Ilmu Keperawatan
Depositing User: Mrs Zahra Tiata Juna
Date Deposited: 23 Feb 2023 01:14
Last Modified: 23 Feb 2023 01:14
URI: http://repository.unsoed.ac.id/id/eprint/20347

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